38 articles - From Friday Dec 05 2025 to Friday Dec 12 2025
Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…
| Pancreas |
|---|
| Clinical Practice Guidelines for Pancreatic Cancer 2025 From the Japan Pancreas Society: A Synopsis.
These guidelines represent the most comprehensive and standardized resource currently available in Japan for the clinical management of pancreatic cancer. This English synopsis aims to disseminate the 2025 edition of the Japanese Clinical Practice Guidelines for Pancreatic Cancer to a global audience and highlight the Japanese approach to pancreatic cancer care. |
meta-analyses and systematic reviews
| Am J Clin Nutr |
|---|
| Effect of early-life protein supplementation on childhood obesity and related metabolic outcomes: a systematic review and meta-analysis.
There is limited evidence of any impact of protein quantity or quality during complementary feeding on growth or body composition. Given the short-lasting exposures and follow-up times, the long-term metabolic effects of protein supplementation require further investigation. |
| Optimal anthropometric discharge criteria from treatment of wasting: meta-analysis of individual patient data from 34 studies.
Relapse risk is high after successful MAM/SAM treatment. Future research can consider optimization of anthropometric discharge criteria as a strategy to reduce postdischarge relapse risk, weighing the operational and financial tradeoffs associated with any modification. |
| Inflamm Bowel Dis |
| The Risk of Relapse Associated With Discontinuation of 5-Aminosalicylates in Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis.
The discontinuation of oral or rectal 5-ASA monotherapy in patients with UC is associated with an increased risk of relapse. The data for discontinuation of 5-ASA in patients with UC or CD who are on immunomodulators and/or biologics is marginal for a meta-analysis; considering this limitation, these patients do not seem to have an increased risk of relapse upon discontinuation of 5-ASA, suggesting that monitored withdrawal may be a viable strategy. |
RCT, clinical trials, retrospective studies, etc…
| Am J Clin Nutr |
|---|
| Association between size at birth, rapid weight gain in infancy and overweight status among Palestinian refugees under 5 years old: a retrospective cohort study.
Rapid weight gain in infancy, regardless of birth size, is a predictor of childhood overweight/obesity. Exclusive human milk feeding mitigates the risk of rapid weight gain and subsequent overweight/obesity. |
| Breastfeeding duration and maternal weight change through adulthood in a population-based cohort study.
We found a significant association between longer breastfeeding duration per child and lower maternal weight gain through adulthood which was particularly pronounced among mothers with overweight or obesity at age 18 y and among mothers who had their first child ≥1980. |
| Development and validation of a brief Nutrition Security Screener (NSS) for clinical and public health settings.
A brief NSS enables assessment of NI prevalence and barriers to healthy eating in diverse populations, and is independently associated with diet-related disease, informing clinical, public health, and policy efforts to screen for and address NI. |
| Male partner pesticide residue exposure from fruit and vegetable intake in relation to outcomes of infertility treatment: a prospective cohort study.
Intake of FVs with high pesticide residue in males is associated with adverse infertility treatment outcomes with ART, particularly in conventional insemination cycles. Implications for natural fertility are unclear. |
| Proteomics Networks Linking Diet to Cardiometabolic Risk Factors: The Framingham Heart Study.
Our findings highlight proteomic networks potentially linking diet and CVD risk and demonstrate the usefulness of proteomics for identifying high-risk individuals for future interventions. |
| Inflamm Bowel Dis |
| Black and Latino/a Participants With Inflammatory Bowel Disease Are More Likely to Be at Risk for Post-Traumatic Stress Than Their White Counterparts: A Matched Control Comparison Study.
Black and Latino/a IBD patients may have rates of IBD-PTS 2.5 times higher than White peers, with more severe PTSD symptoms. Prior nonmedical adverse life events may be risk factors for the development of IBD-PTS. Additional research is warranted. |
| Bowel Wall Thickness Cutoff Value for Assessing Inflammatory Bowel Disease Activity Using Intestinal Ultrasonography in Children.
Although IUS is an excellent tool for detecting moderate/severe bowel inflammation, this method showed limited accuracy in children <6 years old. The adult BWT cutoff missed over 30% of bowel inflammation in children. BWT cutoff of 0.27-0.30 cm in boys and 0.23-0.25 cm in girls and/or children <40 kg indicated active gut inflammation. |
| Characterization of Computed Tomography Colonography Findings of Ulcerative Colitis-Associated Neoplasia.
and relevance Despite preoperative awareness of UCAN, CTC demonstrated limited sensitivity. While CTC may serve a complementary role in selected cases, endoscopy remains essential for comprehensive lesion detection. |
| Real-World Outcomes of Glucagon-Like Peptide-1 Receptor Agonist Therapy in Obese Patients With Ulcerative Colitis and IPAA With a History of Pouchitis.
Our study in a small cohort of patients with UC-IPAA and obesity with a history of pouchitis showed that GLP-1RA use was associated with decreased risk of recurrent pouchitis and anti-diarrheal medication use. |
| Thromboembolic Risk in Ulcerative Colitis Patients on Advanced Therapy: A Real-World Data Analysis.
Vedolizumab demonstrated a favorable thromboembolic and cardiovascular safety profile compared with TNF inhibitors, whereas tofacitinib did not increase the risk at either dose. Concomitant 5-aminosalicylic acid may have a preventive effect against VTE. These findings may aid therapeutic decision-making for UC patients with elevated thrombotic risk. |
| Trends in Use of Prescribed Opioids in Incident and Prevalent Patients With Ulcerative Colitis: A Nationwide Study in Sweden.
In this nationwide register-based study, adults with UC had higher prescribed opioid use within two years before and up to five years after first UC diagnosis compared with reference individuals. However, adults with prevalent UC (and reference individuals) had a declining temporal opioid use trend during 2006-2022. |
| J Crohns Colitis |
| Efficacy and Safety of Risankizumab in Patients with Moderately to Severely Active Crohn's Disease: Interim Results from the SEQUENCE Open-Label Extension Study.
This interim analysis of continuous open-label risankizumab therapy showed durable long-term clinical efficacy and no new safety signals in patients with moderately to severely active Crohn's disease. Future analyses will evaluate longer-term clinical and endoscopic outcomes and safety. Clinical trial registration |
| Identification of Crohn's disease subtypes in single cell RNA sequencing signatures of treatment naïve samples across the paediatric gastrointestinal tract.
Tensor decomposition stratified donors into clinically meaningful groups based on their transcriptomic profile, suggesting these signatures can be utilized for personalized medicine. |
| Liver Transpl |
| Histological findings in follow-up liver biopsies up to 15 years after pediatric liver transplantation: Associations with subclinical rejection, fibrosis, and immunological markers.
DSA-II were associated with SACR (p=0.03) but not with fibrosis or C4d. These findings highlight the importance of protocol biopsies for detecting silent graft injury and guiding individualized immunosuppression in pediatric liver transplant recipients. |
| Severity of liver disease is associated with cirrhotic cardiomyopathy: A multicenter study.
Among patients with cirrhosis who were LT candidates, severity of liver disease was positively associated with the presence of CCM and its echocardiographic features. These data may inform patient selection and encourage early detection of CCM among patients with cirrhosis. |
| The survival benefit of deceased donor liver transplantation using MELD 3.0: A contemporary analysis.
However, MELD 3.0 alone does not capture the full complexity of LT candidacy. Factors such as refractory ascites, hepatic encephalopathy, frailty, and poor quality of life should also be considered when considering LT for the individual patient. |
| Pancreas |
| Episodic and Long-Term Costs of Acute Pancreatitis Requiring Hospitalization among Adults in US Clinical Practice.
The cost of AP requiring hospitalization is high, for the treatment of both acute disease as well as associated long-term complications, which underscores the potential economic benefits from the prevention of this condition. |
| Nimotuzumab Plus Gemcitabine-based Adjuvant Chemotherapy for Resectable Pancreatic Cancer: A Retrospective Observational Study.
By adding nimotuzumab to existing gemcitabine-based AC regimens, RPC patients would show a survival benefit trend with a satisfactory safety profile. |
| Serum Calcium and Hospital Stay in Acute Pancreatitis: A Nonlinear Association With an Inflection Point.
Above 2.5 mmol/L, a significant positive effect emerged. The study also identified significant effect size variations across different subgroups, including sex, age, BMI, and comorbidities. |
| Pancreatology |
| Clinical features and evolution of paraduodenal (groove) pancreatitis: A multicenter study.
Alcohol consumption and smoking are major risk factors for PP. Diabetes and PEI commonly develop in these patients. Conservative treatment strategies are often successful. |
| Cost-effectiveness of biodegradable pancreatic stents in post-ERCP pancreatitis prophylaxis.
BDS for PEP prophylaxis is cost effective compared to conventional PS, avoiding the need for follow-up imaging and repeat procedures for stent removal. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Am J Clin Nutr |
|---|
| Discharge criteria for treatment of wasting: thinking beyond anthropometry. |
| Does higher protein intake influence risk of child obesity? |
| Nutrition security: considerations for a new measure and beyond. |
| Pancreatology |
| The "fat" fad in acute pancreatitis: Healing pancreas with fat. |
misc publications eg case reports, tools of the trade, images of the month, etc…
| Inflamm Bowel Dis |
|---|
| Combination Therapy With Fecal Microbiota Transplantation and Vedolizumab for Induction of Remission in Ulcerative Colitis: An Open-Label Pilot Study. |
| Evaluating Choice of Biologics for Isolated Small-Bowel Crohn's Disease. |
| Liver Transpl |
| Letter to the Editor: Cardiac dysfunction, N-terminal pro-B-type natriuretic peptide and acute-on-chronic liver failure: Inflaming tensions? |
| Letter to the Editor: Tackling the learning curve for safe robotic living donor hepatectomy. |
| Reply: Tackling the learning curve for safe Robotic Living Donor Hepatectomy. |
| Pancreatology |
| Can negative lymph node involvement and resection-free margins (ypT1-3N0R0) complete the disease-free survival benefit of a pathologic complete response (ypT0N0R0) in resected pancreatic cancer post neoadjuvant treatment? |
Letters to the editors and authors’ replies
| Am J Clin Nutr |
|---|
| Nutrition and physical function in aging: measurement and modeling considerations. |
| Inflamm Bowel Dis |
| Exploring the EPIcenter of VEOIBD: defining the genetic drivers of intestinal epithelial cellular dysfunction-authors' reply. |
| Reply: "Early Switching to Subcutaneous Infliximab as a Pragmatic Strategy for Optimized Inflammatory Bowel Disease Care". |